
Leonard M. McEwen
Pioneering Allergist & Developer of Enzyme Potentiated Desensitization (EPD)
Dr. Leonard M. McEwen was a distinguished British clinical and academic allergist, best known for developing Enzyme Potentiated Desensitization (EPD) in the 1960s. His groundbreaking work revolutionized the treatment of allergies, food sensitivities, and autoimmune disorders by introducing an innovative approach that utilized extremely low doses of allergens combined with the enzyme beta-glucuronidase to modulate immune response.
Dr. McEwen's research and clinical trials demonstrated that EPD could effectively stimulate the production of T-regulatory cells, which help correct immune system misidentifications that lead to allergic and autoimmune conditions. His method offered a highly effective and long-lasting alternative to traditional desensitization therapies, leading to significant improvements in patient outcomes.
In the 1990s, Dr. McEwen’s work gained international recognition, leading to large-scale studies in the United States and Canada. His contributions laid the foundation for modern advancements in low-dose allergen immunotherapy, influencing practitioners and researchers worldwide.
Dr. McEwen's legacy continues through the adaptation of his work, particularly in Low Dose Allergen (LDA) Therapy, which builds upon the principles he established. His dedication to improving patient care and advancing immunotherapy remains a cornerstone of allergy treatment today.